M K Wedel Selected Research

alicaforsen

5/2006	Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial.
5/2006	A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis.
5/2006	Bioavailability and therapeutic activity of alicaforsen (ISIS 2302) administered as a rectal retention enema to subjects with active ulcerative colitis.
11/2004	A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis.

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M K Wedel Research Topics

Disease

4	Ulcerative Colitis 05/2006 - 11/2004
2	Pouchitis 05/2006 - 05/2006

Drug/Important Bio-Agent (IBA)

4	alicaforsenIBA 05/2006 - 11/2004
2	Antisense OligonucleotidesIBA 05/2006 - 05/2006
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 05/2006 - 05/2006
1	Proteins (Proteins, Gene)FDA Link 05/2006
1	Mesalamine (Mesalazine)FDA LinkGeneric 05/2006

Therapy/Procedure

4	Enema (Enemas) 05/2006 - 11/2004